ANTI-IDIOTYPIC MRNA VACCINE TO TREAT AUTOIMMUNE DISORDERS

Anti-Idiotypic mRNA Vaccine to Treat Autoimmune Disorders

The 80+ existing autoimmune ASCORBIC ACID disorders (ADs) affect billions with little prevention or treatment options, except for temporary symptomatic management, leading to enormous human suffering and a monumental financial burden.The autoantibodies formed in most ADs have been identified, allowing the development of novel anti-idiotypic antibod

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Feasibility of a tapering opioids prescription program for trauma patients at high risk of chronic consumption (TOPP-trauma): protocol for a pilot randomized controlled trial

Abstract Background Opioid use disorder (OUD) and deaths related to the chronic use of opioids have increased significantly over the last two decades.Chronic consumption of opioids has been documented in many patients with traumatic injuries.Preliminary research findings have shown that interventions using cognitive-behavioral strategies were a pro

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Issues of Improving the Provisions of the Current Law of Ukraine Regarding the Prevention of the Origin and Spread of COVID-19 Coronavirus Disease

The author has studied the current state of the regulatory base on the prevention of the occurrence and spread of the COVID-19coronavirus disease in Ukraine and the practice of its application by authorized entities for the implementation of state policy in the field of health care and the protection of the rights and freedoms of citizens.The syste

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Age-related changes in somatic condition and reproduction in the Eurasian beaver: Resource history influences onset of reproductive senescence.

Using 15 years of data from a stable population of wild Eurasian beavers (Castor fiber), we examine how annual and lifetime access to food resources affect individual age-related changes in reproduction and somatic condition.We found an age-related decline in annual maternal reproductive output, after a peak at age 5-6.Rainfall, an established nega

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